Angio-Seal™ VIP​
Vascular Closure Device
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Angio-Seal™ VIP is indicated for use in closing and reducing time to hemostasis at the common femoral arterial puncture site.
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Simple1 : 3-step deployment
Proven2,3,4
Fast Sealing5,6
Angio-Seal™ VIP Vascular Closure Device
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Angio-Seal™ VIP Vascular Closure Device is designed for sealing the common femoral arterial puncture site (lumen diameter greater than 4 mm) after diagnostic angiography or interventional procedures.

Angio-Seal™ VIP Vascular Closure Device is available in two sizes, providing flexibility for various femoral access procedures using ​

  • an 8 French or smaller procedural sheath for the 8Fr Angio-Seal™ VIP device
  • or a 6 French or smaller procedural sheath for the 6Fr Angio-Seal™ VIP device.

It is designed to help reduce time to hemostasis and to support early ambulation.

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Explore the Clinical Evidence Behind the Angio-Seal™ VIP Vascular Closure Device
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View all Clinical Evidences
View all Clinical Evidences
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Watch the Angio-Seal™ VIP in action
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How to easily deploy the Angio-Seal™ VIP Vascular Closure Device in 3-step?

​STEP 1 : LOCATE THE ARTERY*

  1. Insert the arteriotomy locator into the Angio-Seal™ VIP insertion sheath (arrow to arrow), so the two pieces snap together securely. Insert the Angio-Seal™ VIP guidewire into the procedural sheath, then remove the procedural sheath.
  2. Thread the Angio-Seal™ VIP assembly over the guidewire: when the tip of the insertion sheath is about 1.5 cm into the artery, blood will begin to flow from the drip hole in the locator.

*Assess the puncture site location by performing an angiogram.

STEP 1 : LOCATE THE ARTERY*

3. Confirm proper location by withdrawing the Angio-Seal™ VIP assembly until blood stops flowing from the drip hole, then advance the Angio-Seal™ VIP assembly again until blood begins to flow from the drip hole.

4. Thread the Angio-Seal™ VIP assembly over the guidewire: when the tip of the insertion sheath is about 1.5 cm into the artery, blood will begin to flow from the drip hole in the locator.

*Assess the puncture site location by performing an angiogram.

STEP 2 : SET THE ANCHOR

  1. To release the anchor: carefully grasp the Angio-Seal™ VIP device at the bypass tube and advance it in small increments in the sheath cap until they snap together (arrow to arrow).
  2. To set the anchor: holding the insertion sheath cap steady, grasp the device cap and slowly pull back until resistance from the anchor catching on the distal tip of the insertion sheath is felt. The device sleeve-colored bands should now be completely visible.

STEP 3: SEAL THE PUNCTURE

  1. Withdraw slowly the assembly along the angle of the puncture tract to position the anchor against the vessel wall. A resistance should be felt.
  2. Withdraw the assembly until all the suture has been deployed: a tamper tube will appear when the insertion sheath clears the skin, and a clear stop appears on the suture.

STEP 3: SEAL THE PUNCTURE

3. Advance the knot and collagen with the tamper tube, while maintaining tension on the suture. Hold the tamper tube on the knot for hemostasis. A complete seal is indicated when resistance is felt, and hemostasis is achieved. As a guide, in most cases a compaction marker will be revealed.

4. Cut the suture below the clear stop, then remove the tamper tube.

5. Gently pull up on the suture and cut the suture below skin level. Clean puncture site and apply a sterile dressing so that it can easily be observed during recovery.

What Makes Angio-Seal™ VIP a Simple, Proven, Fast Sealing Vascular Closure Device for Femoral Access Site Management?
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BIOABSORBABLE  - Active arteriotomy closure for effective femoral access site management

The Angio-Seal™ VIP Vascular Closure Device features three components designed for active arteriotomy closure at the femoral access site:

  • Bioabsorbable anchor that is positioned on the inside of the artery
  • Bioabsorbable collagen plug that seals the arteriotomy from the outside
  • Bioabsorbable suture that holds the anchor and plug securely in place

Angio-Seal™ VIP is designed to support safe and effective femoral access site closure7:

  • Complete bioabsorption – all components are fully resorbed within 90 days8
  • Preserves arterial flow – no evidence of chronic scar tissue or inflammation8
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PROVEN - 20+ Years of Reliable Femoral Access Site Management2,3,4

With over 20 years on the market and supported by numerous randomised clinical trials, the Angio-Seal™ VIP Vascular Closure Device has demonstrated:

  • High deployment success rate9
  • Safe and effective closure of the femoral access site7
  • Lower complication rates compared with manual compression10 and other vascular closure devices2
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FAST SEALING5,6 - Angio-Seal™ VIP Vascular Closure Device Outperforms Manual Compression for Faster hemostasis management

Compared with manual compression, the Angio-Seal™ VIP Vascular Closure Device significantly reduces:

  • Time to hemostasis5,6
  • Time to ambulation5
  • Time to discharge11
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Key Specifications
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Get a quick overview of the Angio-Seal™ VIP Vascular Closure Device specifications, including available sizes, components, storage requirements, and safety features.
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Available sizes and guidewire compatibilities for Angio-Seal™ VIP Vascular Closure Device
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Related Solutions
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Explore our Femoral Solutions
Maintaining femoral proficiency is critical as not all interventions can be done radially. Discover how our solutions can support your femoral practice.
Learn more
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References

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Lucatelli P. Angio-Seal™ VIP® vs. StarClose SE® closure devices: a comparative analysis in non-cardiological procedures.. The Journal of cardiovascular surgery. 2017 Feb;58(1):80-86.
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Jones L.E. et al. Safety and Efficacy of Arterial Closure Devices in an Office-Based Angiosuite. Ann Vasc Surg. 2018 Aug;51:10-17.
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Kreutz R.P. et al Femoral Artery Closure Devices vs Manual Compression During Cardiac Catheterization and Percutaneous Coronary Intervention. J Soc Cardiovasc Angiogr Interv. 2022 Jun 29;1(5):100370
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Goueffic Y. et al. Costs and Budget Impact of Collagen-Based Vascular Closure Device Versus Manual Compression Following Peripheral Endovascular Procedures. Ann Vasc Surg. 2023 Jul:93:64-70.
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Alsheri A.M. et al. Comparison of Angio-Seal™ and manual compression in patients undergoing transfemoral coronary and peripheral vascular interventional procedures. International Journal of Angiology. 2015. 24:133-136
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Martin J.L. et al. A randomized trial comparing compression, Perclose Proglide and Angio-Seal VIP for arterial closure following percutaneous coronary intervention: the CAP trial. Catheter Cardiovasc Interv. 2008 Jan 1;71(1):1-5.
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Wong H.F. et al. Prospective comparison of Angio-Seal vs. manual compression for hemostasis after neurointerventional procedures under systemic heparinization. Am J Neuroradiol. 2013; 34: 397-401.
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Tellez A. et al. In vivo intravascular ultrasound analysis of the absorption rate of the Angio-Seal vascular closure device in the porcine femoral artery. EuroIntervention. 2010 Jan;5(6):731-6.
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Manolis. A.S. et al. Simplified swift and safe vascular closure device deployment without a local arteriogram: Single center experience in 2074 consecutive patients. Indian Heart J. 2016 Jul-Aug;68(4):529-38.
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Tavris D.R. et al. Bleeding and vascular complications at the femoral access site following percutaneous coronary intervention (PCI): an evaluation of hemostasis strategies J Invasive Cardiol. 2012 Jul;24(7):328-34.
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Veasey R.A. et al A randomised controlled trial comparing StarClose and AngioSeal vascular closure devices in a district general hospital - the SCOAST study. International Journal of Clinical Practice, 2008; 62(6), 912–918.

Disclaimer

Not all products are available for sale in all countries. This information is provided only in respect to markets where these products are approved or cleared. Please contact your Terumo local sales representative for more information. Refer to Instructions for Use for contraindications, warnings, precautions and additional information. All brand names are trademarks or registered trademarks owned by TERUMO CORPORATION, its affiliates, or unrelated third parties.

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