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Terumo Interventional Oncology Division presents LifePearl, a precise answer to a challenge in interventional oncology. LifePearl are PEG (polyethylene glycol) embolization microspheres that can be loaded with chemotherapeutic agents (such as Doxorubicin, Irinotecan, Idarubicin and Epirubicin).
LifePearl® microspheres are designed to actively absorb drugs into their matrix2
LifePearl® has a tight calibration which may lead to a more targeted embolisation
Diameter distribution histogram of doxorubicin-loaded microspheres4
Diameter distribution histogram of irinotecan-loaded microspheres5
LifePearl® offers longer time in suspension than:
Longer time in suspension allows smoother embolization procedure without the need for interruption to resuspend the microspheres
LifePearl® loaded with Doxorubicin or Irinotecan offers:
LifePearl® loaded with Epirubicin and Idarubicin offers:
Idarubicin elution from LifePearl reaches plateau in approx. 2 hours at 75%
Epirubicin elution from LifePearl reaches plateau in approx. 5 hours at 35%
Giammaria Fiorentini, Donatella Sarti, Riccardo Carandina, Luca Mulazzani, Cinzia Mincarelli, Roberto Candelari, Renato Argirò, Caterina Fiorentini & Camillo Aliberti
Giammaria Fiorentini, MD, Donatella Sarti, PhD, Camillo Aliberti, MD, Riccardo Carandina, MD, Luca Mulazzani, MD, Alessandro Felicioli, MD, Stefano Guadagni, MD
Lucatelli et al.
Please quote above item reference codes when placing an order.
LifePearl is not available for sale in all countries. This information is provided only in respect to markets where this product is approved or cleared. LifePearl is cleared in US with indications for embolization of hyper vascular tumors and arteriovenous malformations. LifePearl is not approved in Canada. Please contact your Terumo local sales representative for more information.
1 LifePearl Instructions for Use (January 2018)2 Data on file. Comparison with Terumo's previously commercialized product. Ref LPMCV-0043 Data on file. Ref LPBTG-002, LPMCV-003, LPMCV-004. Microvention Inc. Comparison with Terumo's previously commercialized product4 Thierry de Baere, et al. An In Vitro Evaluation of Four Types of Drug-Eluting Microspheres Loaded with Doxorubicin. J Vasc Interv Radiol. 2016 Sep;27(9):1425-14315 Philippe L. Pereira, et al. An in-vitro evaluation of three types of drug-eluting microspheres loaded with irinotecan Anti-Cancer Drugs: October 2016 - Volume 27 - Issue 9 - p 873–8786 Data on file. Comparison with Terumo's previously commercialized product. Ref. TR16-1587 Data on file. Ref TR14-286 Microvention Inc. Comparison with Terumo's previously commercialized product
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