Smaller hollow fiber with high efficiency
Hollow fiber is the heart of the oxygenator. With decades of experience of in-house hollow fiber development and manufacturing, Terumo now created a smaller hollow fiber with higher efficiency. This innovative hollow fiber – woven in a unique pattern – provides low priming volume and surface area reduction while delivering high gas exchange performance in combination with a lower transmembrane pressure drop.
Lower priming volume
- Minimizes hemodilution – resulting in fewer red blood cell (RBC) transfusions, which are associated with infection, ischemic postoperative morbidity, longer hospital stays, and higher hospital costs3
- Maintains higher hematocrit – potentially educing acute kidney injury (AKI)4,5
Less foreign surface area
- Reduces risk of inflammatory reaction6
Highly efficient heat exchange
Terumo‘s choice of polymer material and small capillary design increases performance in warming and cooling.2 Clinicians can be confident in the heat exchanger‘s efficiency with the benefit of low prime in a smaller device.
Innovative air removal technology
Plastic heat exchangers retain air bubbles in the spaces between the heat exchange layers. Leveraging our own hollow fiber technology, Terumo has developed a new patent-pending pre-heat-exchanger air removal technology. This technology in combination with our original self-venting technology and Prime Assist™ feature ensures excellent GME removal.
Pre-heat-exchanger air removal technology
- Removes air and prevents it from becoming trapped in the heat exchanger – reducing the potential for inflammatory reactions7
Proven self-venting technology and integrated arterial filter
- Provides the safety2 of arterial filtration with less foreign surface area and no added prime volume – simplifying the circuit and assuring that the oxygenator is fully primed
Prime AssistTM feature
- Enables easier prime – efficiently removing air without tapping and manipulation
References
1. Gomez D et al. Evaluation of air handling in a new generation neonatal oxygenator with integral arterial fi lter Perfusion 2009; 24:107-112.
2. Internal testing, data on file.
3. Murphy GJ et al. Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery. Circulation 2007; 116:2544-2552.
4. Ranucci M et al. Effects of priming volume reduction on allogeneic red blood cell transfusions and renal outcome after heart surgery. Perfusion 2015; 30:120-126.
5. Ranucci M et al. Acute kidney injury and hemodilution during cardiopulmonary bypass: a changing scenario. Ann Thorac Surg. 2015; 100:95-100.
6. Day JR, Taylor KM. The systemic infl ammatory response syndrome and cardiopulmonary bypass. Int J Surg. 2005; 3:129-140.
7. Barak M, Katz Y. Microbubbles: pathophysiology and clinical implications. Chest 2005; 128:2918-2932.
