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Mastering Rapid and Healthy Vascular Repair

13/01/2016 - Global

Pushing the boundaries of science and medical engineering for the improvement of health: Ultimaster combines an optimal balance between stent design for ultimate conformability with simultaneous polymer resorption and drug release, to match the procedure-triggered biological response in the vessel.(1) This results in optimal vessel recovery and potentially shortened DAPT time.(2)

Functional endothelium(3)

1 Month

2 Months

3 Months


86% strut coverage as early as 1 month(4)

translated into long-term safety(6)
















(1) Data on file at Terumo Corporation (Doc nr. BioRes02-T)
(2)1 month DAPT CE Mark approved for patients in need. Patients should be maintained on clinically adequate post-procedural antiplatelet therapy according to the current guidelines. In case of need, dual antiplatelet therapy can be discontinued earlier, but not before one month. Ultimaster IFU
(3) Stojkovic S et al. Reduced sirolimus systemic exposure and improved bioresorbable polymer properties: new allies for the treatment of patients with coronary artery disease. Fundam Clin Pharmacol. 2015 Feb;29(1):95-105
(4) P. Smits et al. DISCOVERY 1TO3 - Assessment of strut coverage of biodegradable polymer DES at 1, 2 and 3 months after stent implantation by Optical Frequency Domain Imaging. Presented at EuroPCR 2015.
(5) Barbato E et al. A first-in-man clinical evaluation of Ultimaster, a new drug-eluting coronary stent system: CENTURY study. EuroIntervention. 2015 Sep 22;11(5):541-8. doi: 10.4244/EIJY14M08_06.
(6) Based on ST rates from CENTURY and CENTURY II trials, Ultimaster IFU and data on file at Terumo Corporation
(7) Saito S et al. A randomized, prospective, intercontinental evaluation of a bioresorbable polymer sirolimus-eluting coronary stent system: the CENTURY II (Clinical Evaluation of New Terumo Drug-Eluting Coronary Stent System in the Treatment of Patients with Coronary Artery Disease) trial. Eur Heart J. 2014 Aug 7;35(30):2021-31