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01/01/2015 -  

60 MVD patients with OFDI, single arm, primary endpoint TLF @ 12M. Ongoing.

Designed to:

  • assess endothelial coverage at 1, 2 and 3 months by OFDI in patients with multivessel disease scheduled for staged PCI procedure
  • provide a "look" in the artery with OFDI after implantation of Ultimaster
  • investigate possibility for shorter DAPT by generating relevant clinical scientific data


Study Design

  • single arm
  • 60 patients with planned staged PCI at 1M/3M
  • Total of 6 sites
  • 3 countries: France, Germany, Netherlands
  • Primary endpoint: OFDI assessed % stent strut coverage at 3M post procedure

Hypothesis: < 20% uncovered struts at 3M post procedure

DISCOVERY 1TO3 - Study Design