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The product is the first made-in-Japan DES which received approval for its manufacture and sale, based on the clinical trials conducted in Japan.

"Nobori" is the only product in Japan that employs bioresorbable polymer as its drug coating material. In addition, polymer and drug are applied only to the surface to contact vessel tissues.

Terumo Corporation received CE certificate*1 for the commercial sale of the "Nobori" in Europe, in January 2008. It is currently sold in more than 20 countries in Europe, Asia (excluding Japan) and Latin America.

*1: The CE Mark indicates that the product satisfies requirements of EU Directives (EU：The European Union) and all products need to be CE certified to be sold in Europe.

A stent is an implant device used in the treatment of angina pectoris, myocardial infarction, and other coronary events caused by blood vessels around the heart (coronary artery) that are stenosed or blocked. After expanding coronary artery with a balloon catheter*2, the stent is implanted in a vessel. However, since stenosis may occur after implanting, DES (stent with a drug) systems are often used.

DES is expected to reduce tissue proliferation that may cause restenosis (narrowing of the treated part of the vessel) because its drug is gradually released to surrounding tissues.

*2: A catheter with a balloon attached to its tip

(Notice) Among the information that Terumo discloses, forecasts of financial performance on future projections contain potential risks and uncertainty since these are forecasts on projections made by Terumo based on limited information available at the moment of disclosure. Accordingly, it should be noted that actual results may differ from those forecasts on projections due to various factors. Factors affecting actual results include, but are not limited to, changes in economic conditions surrounding Terumo, fluctuations of foreign exchange rates, and state of competition.