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Angio-Seal™ - Vascular closure device

The inside advantage

​The Angio-Seal vascular closure device uses three bioabsorbable components to actively seal the arteriotomy:

Intravascular: placed against the inside of the vessel wall.

Extravascular: placed on top of the arteriotomy in the tissue tract.

Cinches the anchor and collagen together to form a secure seal.


The Angio-Seal active closure anchor gives you the inside advantage. The anchor creates a mechanical seal from the inside out.

  • The anchor supports proper location for a reliable seal and collagen positioning:1-3
    - 99.7% deployment success1
    - 97.8% hemostasis by device1
  • The anchor and seal are bioabsorbed:
    - Fibrin coats the anchor within hours and becomes totally encapsulated in 7–14 days4
    - Anchor begins to hydrate and soften 24–36 hours after deployment5
    - Anchor is absorbed 95% at 42 days6
    - All components are absorbed within 60–90 days7
  • Arterial flow is not compromised, no evidence of chronic scar tissue or inflammation6, 8

The bioabsorbable Angio-Seal anchor, suture and collagen provide dual security.1-3

  • Fits closely against the arterial wall, leaving blood flow undisturbed with no residual stenosis6
  • Designed to conform to the arteriotomy for confident closure
  • Tethers the anchor and collagen together, providing a secure seal

General Specifications

Content ​ ​​Vascular closure device
​Insertion sheath
​Arteriotomy locator
​70 cm guidewire with "J" straightener
​Units per box10​

Product Illustrations

locate the artery

  • ​Insert the Angio-Seal locator and sheath system over the wire until blood flows through the drip hole in the locator
  • Withdraw and re-insert to confirm correct location into the vessel
  • Remove the locator and wire, leaving the Angio-Seal sheath in place

Set the anchor

  • ​​Insert the Angio-Seal device into the sheath, click into place and click back to deploy and set the anchor

Set the seal

​Angio-Seal Evolution

  • Pullback the device/sheath assembly until reaching the green marker, which automatically compacts the seal
  • Press the button to release the suture
  • Confirm hemostasis and cut the suture

Angio-Seal VIP and STS Plus

  • Pullback the device/sheath assembly until the suture stops
  • Grasp the tamper tube to manually compact until reaching the black compaction marker
  • Confirm hemostasis and cut the suture

Item Specifications


​Item reference​French size​Guidewire diameter (in)



​Item reference​French size​Guidewire diameter (in)


STS Plus

​Item reference​French size​Guidewire diameter (in)









See Also


1Applegate RJ, Turi Z, Sachdev N, et al. The Angio-Seal Evolution Registry: outcomes of a novel automated Angio-Seal vascular closure device. J Invasive Cardiol. 2010;22(9):420-6.
2 Kussmaul WG, Buchbinder M, Whitlow PL, et al. Rapid arterial hemostasis and decreased access site complications after cardiac catheterization and angioplasty: Results of a randomized trial of a novel hemostatic device. JACC. 1995;25(7):1685-92.
3 Angio-Seal Instructions for Use.
4 Kensey KR. Puncture site hemostasis. J Invasive Cardiol. 1994;6(8):273-6.
5 Angio-Seal PMA 930038. Section V Technical Information, 55.
6 Tellez A, Cheng Y, Yi GH, et al. In vivo intravascular ultrasound analysis of the absorption rate of the Angio-Seal vascular closure device in the porcine femoral artery. EuroIntervention. 2010;5(6):731-6.
7 Nash JE, Evans DG. The Angio-Seal hemostatic puncture closure device. Herz. 1999;24(8):597-606.
8 Aker UT, Kensey KR, Heuser RR, et al. Immediate arterial hemostasis after cardiac catheterization: Initial experience with a new puncture closure device. Cathet Cardiovasc Diagn. 1994;31(3):228-32.

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