Cookie policy

This site uses cookies to improve your user experience. By using this website, you agree that we can place cookies on your device. For further information, please read our Privacy And Cookies Policy

I accept the terms and conditions
Skip Ribbon Commands
Skip to main content

TCD-10023PK Trial

31/05/2013 -  

20 patients, single arm, pharmocokinetics. PCR 2013.

​​

Results

1. Sirolimus Concentration

Very low concentration of drug in peripheral circulation

TCD-10023PK - Primary Endpoint


2. Preserved endothelial function in stented human coronary arteries

TCD-10023PK - Target Lesion Failure

Vasomotor pattern of target and reference vessels at baseline, maximal atrial pacing and after nitrates given in the vessel segment distal to the study stent.

Stojkovic et al. Fundam Clin Pharmacol. 2014 Sep 16. doi: 10.1111/fcp.12092. [Epub ahead of print]